Call your doctor if you have severe joint pain. Tell your doctor right away if you develop blisters or the breakdown of the outer layer of your skin erosion. If you take JANUVIA with another medicine that can cause low blood sugar hypoglycemia , such as a sulfonylurea or insulin, your risk of getting low blood sugar is higher.
Signs and symptoms of low blood sugar may include headache, drowsiness, irritability, hunger, dizziness, confusion, sweating, feeling jittery, weakness, and fast heart beat. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www. The physician Prescribing Information also is available. Having trouble paying for your Merck medicine? Merck may be able to help. Visit merckhelps. This section contains information intended for health care professionals in the United States only and is not intended for the general public.
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JANUVIA is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. If you have had pancreatitis inflammation of the pancreas in the past, it is not known if you have a higher chance of getting pancreatitis while you take JANUVIA.
When your body is under some types of stress, such as fever, trauma such as a car accident , infection or surgery, the amount of diabetes medicine that you need may change. Check your blood sugar as your doctor tells you to. Talk to your doctor about how to prevent, recognize and manage low blood sugar hypoglycemia , high blood sugar hyperglycemia , and problems you have because of your diabetes.
Your doctor will check your diabetes with regular blood tests, including your blood sugar levels and your hemoglobin A1C. Signs and symptoms of low blood sugar may include: headache drowsiness irritability hunger dizziness confusion sweating feeling jittery weakness fast heart beat.
Always talk to your doctor before starting an exercise program. Certain medical problems make you more likely to get pancreatitis Before you start taking JANUVIA, tell your doctor if you have ever had: pancreatitis high blood triglyceride levels stones in your gallbladder gallstones kidney problems a history of alcoholism Stop taking JANUVIA and call your doctor right away if you have pain in your stomach area abdomen that is severe and will not go away.
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By Consumer Reports. Last updated: December 30, Sharing is Nice Yes, send me a copy of this email. Send We respect your privacy. Oops, we messed up. In 19 clinical studies , 0. This is a swelling of the pancreas, the organ that creates the hormone insulin.
When your pancreas is swollen, your body may not be able to make insulin as well. Your doctor may have you stop taking Januvia and may prescribe a different medication. But there have been concerns about whether Januvia may increase your chance of developing pancreatic cancer. A clinical study looked at the health history of 71, people who took Januvia. In this group, 83 people developed pancreatic cancer. Further studies are needed to confirm a link between Januvia and an increased chance of developing pancreatic cancer.
The Food and Drug Administration FDA has alerted healthcare providers about the possible link and is investigating further. Januvia rarely causes hypoglycemia low blood sugar when taken by itself. In clinical studies , 1.
But when Januvia is combined with other medications that treat diabetes, the risk of hypoglycemia increases. Hypoglycemia can cause less sugar to go to your cells and organs, which can make them not work as well.
In clinical studies , In people who took Januvia with the diabetes drug glimepiride, the rate of hypoglycemia was They may adjust your dose of Januvia or other diabetes medications to control the amount of sugar in your blood.
However, according to the FDA , diabetes drugs similar to Januvia, including Onglyza and Nesina, have been shown to increase the risk of heart failure. These medications are in the same class as Januvia and have similar effects in your body. Tell your doctor if you have a history of heart failure. They may adjust your treatment and prescribe a medication other than Januvia. No clinical trials of Januvia reported cancer as a side effect. However, a study in Taiwan found that people who took Januvia had a higher chance of developing thyroid cancer.
Yet no clinical studies in the United States have linked Januvia to thyroid cancer. Interestingly, some evidence shows that Januvia may have a positive effect on other types of cancer. Three more studies in Taiwan, such as this study , suggest that taking Januvia may reduce the chance of developing oral cancer, breast cancer, and prostate cancer.
Pain in your joints is a possible side effect of taking Januvia. Joint pain is also a side effect of diabetes drugs that are similar to Januvia. More studies are needed to know the specific risk of having joint pain while taking Januvia. If you have sore joints, let your doctor know. They can recommend treatments to help you feel more comfortable. Or they might have you stop taking Januvia and use another diabetes medication instead. However, some studies have shown that people who took Januvia with other diabetes drugs did have diarrhea.
This included people who took metformin, which is a common cause of diarrhea. If you have diarrhea while taking Januvia and other diabetes drugs, drink a lot of water.
Call your doctor if the diarrhea lasts longer than three days. Your doctor can recommend treatments to help ease your symptoms. They may also adjust the dosage of your diabetes medications. No clinical studies have linked the use of Januvia to kidney problems.
But some people have reported kidney problems after taking Januvia, including kidney failure. Also, kidney problems may limit the amount of Januvia that leaves your body. This may increase the amount of Januvia in your blood and lead to severe side effects. If you have or had any kidney problems, let your doctor know right away. Also, tell your doctor if you have symptoms of kidney failure.
These can include pain or pressure in your chest or swelling of your legs, ankles, and feet. Before and while you take Januvia, your doctor will give you blood tests to see how your kidneys are working. However, skin rashes can be a symptom of an allergic reaction to Januvia. If you notice a rash on your skin, let your doctor know. They can recommend treatments to help ease your symptoms. Your doctor may also have you stop taking Januvia and use a different medication instead.
However, people who took Januvia with other diabetes drugs did have edema. Symptoms of edema can include swelling in some parts of your body, such as your hands and legs.
In a clinical study , 8. This was compared to 5. In some cases, edema may be temporary and will go away on its own. They can recommend treatments to ease your symptoms.
Your doctor may also adjust the dosage of your diabetes medications. However, other studies have looked at whether Januvia may help people lose weight. In one small clinical study , people with high cholesterol who took Januvia to treat their type 2 diabetes lost about 18 lbs. They may adjust your diet and exercise routine based on your needs.
They may also recommend a dietitian to help make sure you get proper nutrition. After taking Januvia for three months, they lost 6. In some cases, your doctor may want you to take insulin along with Januvia. They may adjust your diet and exercise routine as needed. No clinical studies have linked the use of Januvia with constipation. Type 2 diabetes can also cause constipation. If you have constipation on a regular basis, let your doctor know.
No clinical studies have linked the use of Januvia with hair loss. But type 2 diabetes may cause hair loss in some people. Your doctor may also give you tips on how to cope with hair loss. No clinical studies have linked the use of Januvia with erectile dysfunction ED. But type 2 diabetes may cause ED in some men. Typically, your doctor will start you on a low dosage.
Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you.
Your doctor will determine the best dosage to suit your needs. Januvia is typically prescribed in dosages of mg, once a day. Differences in dosages can be more common in older adults.
This is because their kidneys may work less well as they age. It may help to take your medication at the same time each day so it becomes routine.
Consider using them if you have problems remembering when to take Januvia. Januvia is meant to be used as an ongoing treatment.
If you need financial support to pay for Januvia, or if you need help understanding your insurance coverage, help is available. Merck, the manufacturer of Januvia, offers savings coupons to help lower the cost of Januvia. Januvia is FDA-approved to treat type 2 diabetes, along with diet and exercise. Some of the medications that have been found effective with Januvia include:.
If you have type 1 diabetes or want to lose weight, talk with your doctor. In one clinical study that lasted 18 weeks, Januvia was tested in people with type 2 diabetes.
In a week clinical study of people with type 2 diabetes, Januvia reduced A1C levels 0. Your doctor may recommend that you take Januvia by itself or with other medications that also treat diabetes. Some of these other drugs may include:. Other drugs are available that can treat your condition. Some may be better suited for you than others. They can tell you about other medications that may work well for you. You may wonder how Januvia compares to other medications that are prescribed for similar uses.
Here we look at how Januvia and Tradjenta are alike and different. Januvia and Tradjenta belong to the same class of drugs called dipeptidyl peptidase-4 DPP-4 inhibitors. This means that they work in similar ways in your body. Tradjenta also comes as a tablet that you swallow.
The recommended dosage is 5 mg, once a day. Januvia and Tradjenta both work in the same way. So both medications can cause very similar side effects. Below are examples of these side effects. These lists contain examples of more common side effects that can occur with Januvia, with Tradjenta, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur with Januvia, with Tradjenta, or with both drugs when taken individually.
Januvia and Tradjenta are both FDA-approved to treat type 2 diabetes, along with diet and exercise. Separate studies of the two drugs were compared in a larger review of studies.
Researchers looked at how well Januvia and Tradjenta helped lower A1C levels. This is a measure of how well your blood sugar is controlled over a few months. Januvia was found to be as effective as Tradjenta. Januvia and Tradjenta are both brand-name drugs. There are currently no generic forms of either drug.
Brand-name medications usually cost more than generics. According to estimates on GoodRx. This is because an unacceptable level of a probable carcinogen cancer-causing agent was found in some extended-release metformin tablets. If you currently take this drug, call your healthcare provider. They will advise whether you should continue to take your medication or if you need a new prescription.
In addition to Tradjenta above , metformin is also used to treat type 2 diabetes. Here we look at how Januvia and metformin are alike and different.
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